Interleukin-22 Ameliorates Dextran Sulfate Sodium-Induced Colitis through the Upregulation of lncRNA-UCL to Accelerate Claudin-1 Expression via Sequestering miR-568 in Mice.

Chonghua He Ze-Han Chen Jialan Huang Riyun Gan Jianyao Wang Li-Sheng Wang De-Feng Li Jun Yao

Published in: Oxidative medicine and cellular longevity (2022)

We have demonstrated the incredible role of bioactive compound, such as IL-22, in alleviating DSS-induced colitis symptoms via enhancing lncRNA-UCL expression. It can be regulated using tight junction (TJ) protein.

Keyphrases

poor prognosis
long non coding rna
cell proliferation
long noncoding rna
binding protein
blood brain barrier
transcription factor
mouse model
type diabetes
signaling pathway
metabolic syndrome
high fat diet induced
insulin resistance
sleep quality
depressive symptoms
skeletal muscle