Safety and Effectiveness Outcomes From a 14-Country Cohort of Patients With Multi-Drug Resistant Tuberculosis Treated Concomitantly With Bedaquiline, Delamanid, and Other Second-Line Drugs.
Helena HuergaUzma KhanMathieu BastardCarole D MitnickNathalie LachenalPalwasha Y KhanKwonjune J SeungNara MelikyanSaman AhmedMichael L RichFrancis VaraineElna OssoMakhmujan RashitovNaseem SalahuddinGocha SaliaEpifanio SánchezArmine SerobyanMuhammad Rafi SiddiquiDri Grium TeferaDmitry VetushkoLusine YeghiazaryanDavid HoltzmanShirajul IslamAndargachew KumsaGamarly Jacques LeblancOlga LeonovichShahid MamsaMohammad Manzur-Ul-AlamZaw MyintShrivani PadayacheeMolly F FrankeCatherine HewisonPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Concomitant use of Bdq and Dlm, along with linezolid and clofazimine, is safe and effective for MDR/RR-TB patients with extensive disease. Using these drugs concomitantly is a good therapeutic option for patients with resistance to many anti-TB drugs.