Runx2-I is an Early Regulator of Epithelial-Mesenchymal Cell Transition in the Chick Embryo.
Andre L P TavaresJessie A BrownEmily C UlrichKaterina DvorakRaymond B RunyanPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2017)
These data introduce the RUNX2-I isoform as a critical early transcription factor mediating EMT in the developing heart after induction by TGFβ2. Its expression in tumor tissue suggests a similar role for RUNX2 in the EMT of metastasis. Developmental Dynamics 247:542-554, 2018. © 2017 Wiley Periodicals, Inc.
Keyphrases
- transcription factor
- epithelial mesenchymal transition
- dna binding
- poor prognosis
- transforming growth factor
- stem cells
- single cell
- heart failure
- bone marrow
- genome wide identification
- electronic health record
- cell therapy
- big data
- atrial fibrillation
- binding protein
- machine learning
- pregnant women
- pregnancy outcomes
- mesenchymal stem cells