Clinical value of selected markers of angiogenesis, inflammation, insulin resistance and obesity in type 1 endometrial cancer.
Katarzyna M TerlikowskaBozena DobrzyckaRobert TerlikowskiAnna SienkiewiczMaciej KinalskiSlawomir J TerlikowskiPublished in: BMC cancer (2020)
Our study provides evidence that serum levels of Ang-2 and CRP may serve as predictors for assessment of the clinical stage of type 1 EC and are significantly associated with poor prognosis. It is likely that angiogenesis and inflammation associated with obesity have a significant impact on EC type 1 progression and survival rate of patients.
Keyphrases
- insulin resistance
- poor prognosis
- endometrial cancer
- metabolic syndrome
- type diabetes
- oxidative stress
- high fat diet induced
- long non coding rna
- end stage renal disease
- weight loss
- endothelial cells
- adipose tissue
- high fat diet
- skeletal muscle
- newly diagnosed
- ejection fraction
- chronic kidney disease
- weight gain
- vascular endothelial growth factor
- polycystic ovary syndrome
- prognostic factors
- angiotensin ii
- physical activity
- peritoneal dialysis
- wound healing
- body mass index
- glycemic control
- patient reported outcomes