Discordant Monozygotic Parkinson Disease Twins: Role of Mitochondrial Integrity.

Marija Dulovic-MahlowInke R KönigJoanne TrinhSokhna Haissatou DiawPeter P UrbanEvelyn KnappeNeele KuhnkeLena-Christin IngwersenFrauke HinrichsJoachim WeberPatrycja Kupnicka Alexander BalckSylvie DelcambreTillman VollbrandtAnne Grünewald Christine KleinPhilip SeiblerKatja Lohmann

Published in: Annals of neurology (2020)

We demonstrate disease-related differences in mitochondrial integrity in the genetically identical twins. Of note, the clinical expression matches functional alterations of the mitochondria. ANN NEUROL 2021;89:158-164.

Keyphrases

parkinson disease
deep brain stimulation
oxidative stress
poor prognosis
gestational age
cell death
binding protein
neural network
endoplasmic reticulum
long non coding rna