MMP-2 regulates Src activation via repression of the CHK/MATK tumor suppressor in osteosarcoma.
Deanna V MaybeeChristopher R CromwellBasil P HubbardMohammad A M AliPublished in: Cancer reports (Hoboken, N.J.) (2023)
By targeting the MMP-2 gene, we can potentially enhance the effectiveness of doxorubicin treatment and reduce chemoresistance in osteosarcoma.