The association between irisin and muscle metabolism in different thyroid disorders.
Ariadna Zybek-KocikNadia Sawicka-GutajEwelina Szczepanek-ParulskaMirosław AndrusiewiczJoanna Waligórska-StachuraPiotr BiałasTomasz KrauzePrzemysław GuzikJerzy SkrobiszMarek RuchalaPublished in: Clinical endocrinology (2017)
The presented data support the theory that irisin concentration changes are associated with prolonged hypothyroidism and might primarily constitute the result of prolonged myopathy. These changes are most likely not related to the expression of the FNDC5 gene in the thyroid gland.