Emulating a target trial of proton pump inhibitors and dementia risk using claims data.

Nayeon Ahn Michael NoldeAlexander GünterFlorian GüntnerRoman GerlachMartin TauscherUte AmannJakob LinseisenChrista MeisingerIna-Maria Rückert-EhebergSebastian-Edgar Baumeister

Published in: European journal of neurology (2022)

This study suggests that PPI initiation and time-varying PPI use may increase overall dementia risk.

Keyphrases

mild cognitive impairment
cognitive impairment
health insurance
randomized controlled trial
big data
machine learning