Design and user experience testing of a polygenic score report: a qualitative study of prospective users.

Deanna G BrockmanLia PetronioJacqueline S DronBum Chul KwonTrish VosburgLisa NipAndrew TangMary O'ReillyNiall LennonBang WongKenney NgKatherine H HuangAkl C FahedAmit V Khera

Published in: BMC medical genomics (2021)

Our findings describe a generalizable approach to develop a polygenic score report understandable by potential patients. Although additional studies are needed across a wider spectrum of patient populations, these results are likely to inform ongoing efforts related to polygenic score disclosure within clinical practice.

Keyphrases

clinical practice
end stage renal disease
newly diagnosed
ejection fraction
peritoneal dialysis
patient reported outcomes
genetic diversity
drug induced