Login / Signup

Lipid-laden foam cells in the pathology of atherosclerosis: shedding light on new therapeutic targets.

Cristi L GalindoSaifur KhanXiangyu ZhangYu-Sheng YehZiyang LiuBabak Razani
Published in: Expert opinion on therapeutic targets (2023)
As key players in atherosclerosis, foam cells are attractive targets for developing more specific, targeted therapies aimed at resolving atherosclerotic plaques. Recent advances in our understanding of lipid handling within these cells provide insights into how they might be manipulated and clinically translated to better treat atherosclerosis.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • cardiovascular disease
  • oxidative stress
  • cell death
  • fatty acid
  • cell proliferation