Lipid-laden foam cells in the pathology of atherosclerosis: shedding light on new therapeutic targets.
Cristi L GalindoSaifur KhanXiangyu ZhangYu-Sheng YehZiyang LiuBabak RazaniPublished in: Expert opinion on therapeutic targets (2023)
As key players in atherosclerosis, foam cells are attractive targets for developing more specific, targeted therapies aimed at resolving atherosclerotic plaques. Recent advances in our understanding of lipid handling within these cells provide insights into how they might be manipulated and clinically translated to better treat atherosclerosis.