Obesity and Body Composition in Relation to Liver and Kidney Ultrasound Elastography in Paediatric Patients with Either Hypertension or Chronic Kidney Disease.
Nataša Marčun VardaSonja Golob JančičMirjam MočnikPublished in: Children (Basel, Switzerland) (2023)
(1) Background: Ultrasound elastography is a novel ultrasound technique for evaluating tissue elasticity. One of the key factors influencing the measurement in children is excess weight. This study aimed to evaluate the effect of body composition, namely, fat mass, on liver and kidney ultrasound elastography in paediatric patients. (2) Methods: 114 participants, in whom bioimpedance, along with liver and kidney ultrasound elastography, were performed, were included (37 patients with chronic kidney disease, 46 patients with hypertension, and 31 healthy subjects). (3) Results: Bioimpedance analysis showed a significant correlation between liver elastography parameters and the phase angle ( p = 0.002), fat-free mass ( p = 0.001), body cell mass ( p = 0.001), total body water ( p = 0.001), extracellular water ( p = 0.006), and, to lesser extent, fat mass ( p = 0.041). On the contrary, kidney elastography parameters strongly correlated only with fat mass ( p < 0.001 for both kidneys). (4) Conclusions: Liver and kidney stiffness increased in overweight participants and showed significant correlation with fat mass, particularly in the case of kidney elastography.
Keyphrases
- body composition
- liver fibrosis
- adipose tissue
- magnetic resonance imaging
- chronic kidney disease
- resistance training
- end stage renal disease
- bone mineral density
- weight loss
- blood pressure
- fatty acid
- intensive care unit
- emergency department
- contrast enhanced ultrasound
- ultrasound guided
- weight gain
- peritoneal dialysis
- newly diagnosed
- physical activity
- body mass index
- stem cells
- young adults
- metabolic syndrome
- ejection fraction
- prognostic factors
- computed tomography
- bone marrow
- high resolution
- patient reported outcomes
- arterial hypertension