Loading dose and efficacy of continuous or extended infusion of beta-lactams compared with intermittent administration in patients with critical illnesses: A subgroup meta-analysis and meta-regression analysis.
Chih-Chien WuYi-Chia SuKuan-Sheng WuTung-Ho WuChing-Shiang YangPublished in: Journal of clinical pharmacy and therapeutics (2020)
CEIs with loading-dose treatment may significantly improve the clinical outcomes in critically ill sepsis or septic shock patients.