Design and evaluation of adapalene microemulsion for transfollicular drug delivery through guinea pig skin.
Anayatollah SalimiBehzad Sharif Makhmal ZadehFatemeh Safari AmirabadiPublished in: Journal of cosmetic dermatology (2023)
Furthermore, the proportions of the water and oil phases in formulations, as well as the S/C ratio, have a significant impact on the physicochemical characteristics and adapalene permeability across both pathways.