Early High-Dose Vitamin D3 for Critically Ill, Vitamin D-Deficient Patients.
null nullAdit A GindeRoy G BrowerJeffrey M CaterinoLani FinckValerie M Banner-GoodspeedColin K GrissomDouglas HaydenCatherine L HoughRobert C HyzyAkram KhanJoseph E LevittPauline K ParkNancy RingwoodEmanuel P RiversWesley H SelfNathan I ShapiroB Taylor ThompsonDonald M YealyDaniel TalmorPublished in: The New England journal of medicine (2019)
Early administration of high-dose enteral vitamin D3 did not provide an advantage over placebo with respect to 90-day mortality or other, nonfatal outcomes among critically ill, vitamin D-deficient patients. (Funded by the National Heart, Lung, and Blood Institute; VIOLET ClinicalTrials.gov number, NCT03096314.).