Electroacupuncture alleviates the transition from acute to chronic pain through the p38 MAPK/TNF-α signalling pathway in the spinal dorsal horn.
Ying JinJie ZhouFangfang XuZeqin RenJun HuCong ZhangKaiwen GeLanying LiuPublished in: Acupuncture in medicine : journal of the British Medical Acupuncture Society (2021)
Our findings indicate that EA could increase the mechanical pain threshold in rats and inhibit the transition from acute pain to chronic pain. This mechanism could involve reduced p38 MAPK/TNF-α expression in the spinal dorsal horn.