Medication persistence rates and predictive factors for discontinuation of antifibrotic agents in patients with idiopathic pulmonary fibrosis: a real-world observational study.

Keiji OishiTsunahiko HiranoYoriyuki MurataKazuki HamadaSho UeharaRyo SuetakeYoshikazu YamajiMaki Asami-NoyamaNobutaka EdakuniSyuichiro OhataToshiaki UtsunomiyaKenji SakamotoHideko OnodaTsuneo MatsumotoKazuto MatsunagaMasafumi Yano

Published in: Therapeutic advances in respiratory disease (2020)

PS may be informative for predicting discontinuation of medication. Our data reinforced the importance of early initiation of antifibrotic treatment, and we suggest PS should be used as a guide for starting antifibrotic agents in everyday practice. The reviews of this paper are available via the supplementary material section.

Keyphrases

idiopathic pulmonary fibrosis
pulmonary fibrosis
healthcare
adverse drug
interstitial lung disease
primary care
electronic health record
big data
randomized controlled trial
rheumatoid arthritis
systematic review
quality improvement
machine learning
data analysis
drug induced