Identification phenotypic and genotypic characterization of biofilm formation in Escherichia coli isolated from urinary tract infections and their antibiotics resistance.
Elnaz Davari AbadAmin KhamenehLeila VahediPublished in: BMC research notes (2019)
The frequencies of sfa, afa and foc were 75.3%, 17.5% and 22.5%, respectively showing a significantly higher prevalence of the sfa gene. The most effective antibiotics against the E. colis were nitrofurantoin and amikacin. The highest microbial resistance rates were also observed against amoxicillin and ampicillin. Furthermore, 12.7%, 6.3%, 74.7% and 6.3% of the isolates showed strong, moderate, weak capacities and no connections to form biofilms, respectively. The expression of the sfa gene was significantly associated with forming strong biofilms. Regarding the variabilities in the characteristics of E. coli strains associated with UTIs, it seems reasonable to adjust diagnostic and therapeutic methods according to the regional microbial characteristics.
Keyphrases
- escherichia coli
- biofilm formation
- candida albicans
- urinary tract infection
- microbial community
- pseudomonas aeruginosa
- copy number
- staphylococcus aureus
- genome wide
- poor prognosis
- genome wide identification
- risk factors
- klebsiella pneumoniae
- cystic fibrosis
- high intensity
- dna methylation
- bioinformatics analysis
- transcription factor