Time for a Time Window Extension: Insights from Late Presenters in the ESCAPE Trial.
James W EvansBrett R GrahamP PordeliFahad S Al-AjlanR WillinskyW J MontaneraJeremy L RempelAshfaq ShuaibP BrennanDavid J WilliamsDaniel RoyAlexandre Y PoppeTudor G JovinT DevlinB J BaxterTimo KringsFrank L SilverD F FreiC FanaleDonatella TampieriJeanne TeitelbaumDana IancuJai Jai Shiva ShankarPhilip A BarberAndrew M DemchukMayank GoyalMichael D HillBijoy K Menonnull nullPublished in: AJNR. American journal of neuroradiology (2017)
Patients with an extended time window could potentially benefit from endovascular treatment. Ongoing randomized controlled trials using imaging to identify late presenters with favorable brain physiology will help cement the paradigm of using time windows to select the population for acute imaging and imaging to select individual patients for therapy.
Keyphrases
- high resolution
- endovascular treatment
- end stage renal disease
- randomized controlled trial
- ejection fraction
- chronic kidney disease
- newly diagnosed
- clinical trial
- peritoneal dialysis
- stem cells
- liver failure
- multiple sclerosis
- mass spectrometry
- prognostic factors
- photodynamic therapy
- respiratory failure
- fluorescence imaging
- acute respiratory distress syndrome
- brain injury
- phase iii
- blood brain barrier