Sleep Characteristics and Risk of Stroke and Dementia: An Observational and Mendelian Randomization Study.
Chutian GuoEric L HarshfieldHugh Stephen MarkusPublished in: Neurology (2024)
We found that multiple sleep measures predicted future risk of stroke and dementia, but these associations were attenuated after controlling for cardiovascular risk factors and were absent in MR analyses for Alzheimer disease. This suggests possible confounding or reverse causation, implying caution before proposing sleep disorder modifications for dementia treatment.
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