Lin - CD117 + CD34 + FcεRI + progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti-IgE therapy.

Katie RidgeBarry MoranP Abigail Alvarado-VazquezJenny Hallgren Mark A Little Alan D Irvine Cliona O'FarrellyJean DunneConor M FinlayNiall Conlon

Published in: Allergy (2024)

cells may reflect enhanced bone marrow egress in the setting of CSU. High expression of these cells strongly predicts better clinical responses to the anti-IgE therapy, omalizumab.

Keyphrases

induced apoptosis
bone marrow
cell cycle arrest
poor prognosis
mesenchymal stem cells
cell death
stem cells
cell proliferation