CRISPR/Cas genome editing revealed non-angiogenic role of VEGFA gene in porcine luteal cells: a preliminary report.

Jaya Bharati Satish Kumar Narayana H MohanSeema Rani PeguSanjib BorahVivek Kumar Gupta Mihir Sarkar

Published in: Molecular biology reports (2024)

The ablation of VEGFA gene resulted in decreased steroidogenic capability of luteal cells, which suggests that VEGFA exerts additional non-angiogenic regulatory effects in luteal cell functionality.

Keyphrases

crispr cas
genome editing
induced apoptosis
cell cycle arrest
single cell
genome wide
copy number
endoplasmic reticulum stress
stem cells
gene expression
signaling pathway
cell death
radiofrequency ablation
genome wide analysis