Treatment for Rheumatoid Arthritis Associated With Alterations in the Gastrointestinal Microbiota.
Kristofer AndréassonTor OlofssonVenu LagishettyZaid AlrawiEline KlaassensSavanne HolsterRoger HesselstrandJonathan Patrick JacobsJohan Karlsson WallmanElizabeth R VolkmannPublished in: ACR open rheumatology (2024)
This study affirms that dysbiosis is a feature of RA. Although patients were not randomized to MTX or TNFi, the findings suggest that specific therapies may differentially modulate the gastrointestinal microbiota in RA. The association between P. copri and treatment response requires further study.
Keyphrases
- rheumatoid arthritis
- end stage renal disease
- disease activity
- ejection fraction
- newly diagnosed
- machine learning
- chronic kidney disease
- randomized controlled trial
- interstitial lung disease
- double blind
- clinical trial
- systemic lupus erythematosus
- prognostic factors
- systemic sclerosis
- phase ii
- phase iii
- patient reported outcomes