A PRISMA meta-analysis for diagnostic value of microRNA-21 in head and neck squamous cell carcinoma along with bioinformatics research.

Chen-Xi LiYing SuZheng-Ye WangHui LiuZhong-Cheng GongHua-Rong Zhao

Published in: Oral and maxillofacial surgery (2023)

This study is the highest level of evidence presently available in diagnosing HNSCC. This PRISMA meta-analysis indicated that the pooled results were robust, confirming the oncogenic potential of miR-21 that could be used successfully as a screening biomarker in HNSCC patients. Specifically, the overexpression of miR-21 in these patients presents a worse survival outcome.

Keyphrases

systematic review
end stage renal disease
cell proliferation
ejection fraction
chronic kidney disease
meta analyses
long non coding rna
prognostic factors
peritoneal dialysis
randomized controlled trial
risk assessment
climate change