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An ensemble machine learning model based on multiple filtering and supervised attribute clustering algorithm for classifying cancer samples.

Shilpi BoseChandra DasAbhik BanerjeeKuntal GhoshMatangini ChattopadhyaySamiran ChattopadhyayAishwarya Barik
Published in: PeerJ. Computer science (2021)
To assess the performance of the proposed MFSAC-EC model, it is applied on different high-dimensional microarray gene expression datasets for cancer sample classification. The proposed model is compared with well-known existing models to establish its effectiveness with respect to other models. From the experimental results, it has been found that the generalization performance/testing accuracy of the proposed classifier is significantly better compared to other well-known existing models. Apart from that, it has been also found that the proposed model can identify many important attributes/biomarker genes.
Keyphrases
  • machine learning
  • gene expression
  • deep learning
  • papillary thyroid
  • systematic review
  • randomized controlled trial
  • dna methylation
  • artificial intelligence
  • squamous cell carcinoma
  • big data
  • genome wide
  • neural network