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Cardiac safety of trabectedin monotherapy or in combination with pegylated liposomal doxorubicin in patients with sarcomas and ovarian cancer.

Robin L JonesThomas J HerzogShreyaskumar R PatelMargaret von MehrenScott M SchuetzeBrian Andrew Van TineRobert L ColemanRoland KnoblauchSpyros TriantosPeter HuWaleed ShalabyTracy McGowanBradley J MonkGeorge D Demetri
Published in: Cancer medicine (2021)
For patients with STS or ROC who still have limited treatment options, trabectedin may be initiated after carefully considering benefit versus risk. Trial Registration (ClinicalTrials.gov): NCT01343277; NCT00113607; NCT01846611.
Keyphrases
  • clinical trial
  • phase iii
  • study protocol
  • open label
  • left ventricular
  • drug delivery
  • phase ii
  • cancer therapy
  • randomized controlled trial
  • heart failure
  • atrial fibrillation