Efficacy of Silexan in patients with anxiety disorders: a meta-analysis of randomized, placebo-controlled trials.

Markus DoldLucie BartovaHans-Peter VolzErich SeifritzHans-Jürgen MöllerSandra SchläfkeSiegfried Kasper

Published in: European archives of psychiatry and clinical neuroscience (2023)

This meta-analysis demonstrates that Silexan exerts significant anxiolytic effects in subthreshold anxiety, GAD and MADD that were consistently reflected in investigator ratings and patient-reported outcomes, including improvement of health-related life-quality, while showing favorable tolerability and safety.

Keyphrases

placebo controlled
patient reported outcomes
double blind
systematic review
phase iii
phase ii
open label
clinical trial
phase ii study
study protocol
meta analyses
randomized controlled trial
quality improvement
squamous cell carcinoma
physical activity
rectal cancer
radiation therapy