The expression of lncRNAs CASC2, NEAT1, LINC00299 in breast cancer tissues and their relationship with the XBP1 splicing rate in Iranian patients during 2014-2019: A cross-sectional study.
Ghazal OrakHossein Babaahmadi RezaeiFereshteh AmeliFatemeh MaghsoodiMaryam CheraghzadeMaryam AdelipourPublished in: Health science reports (2023)
Based on the association between the expression of lncRNAs CASC2, LINC00299, and NEAT1 and the XBP1s/u ratio, these lncRNAs could be potential regulators of the UPR pathway. Also, CASC2 and NEAT1 genes could be suggested as suitable biomarkers to distinguish cancerous tissue from noncancerous breast tissue due to their significant increase in expression in cancerous samples compared to adjacent noncancerous.
Keyphrases
- poor prognosis
- long non coding rna
- end stage renal disease
- cell proliferation
- genome wide identification
- ejection fraction
- newly diagnosed
- binding protein
- long noncoding rna
- chronic kidney disease
- genome wide analysis
- network analysis
- transcription factor
- genome wide
- prognostic factors
- risk assessment
- patient reported