Rationale and design of a multicentre, 12-week, randomised, double-blind, placebo-controlled, parallel-group, investigator-initiated trial to investigate the efficacy and safety of elobixibat for chronic constipation.
Kosuke TanakaTakaomi KessokuAtsushi YamamotoKota TakahashiYuki KasaiAnna OzakiMichihiro IwakiTakashi KobayashiTsutomu YoshiharaNoboru MisawaTakayuki KatoJun ArimotoAkiko FuyukiEiji SakaiTakuma HigurashiHideyuki ChibaKunihiro HosonoMasato YonedaTomoyuki IwasakiTakeo KurihashiMachiko NakatogawaAyao SuzukiMasataka TaguriShunsuke OyamadaKeisuke AriyoshiNoritoshi KobayashiYasushi IchikawaHirokazu TakahashiPublished in: BMJ open (2022)
ClinicalTrials.gov (number NCT04784780).