Regulatory role of miR-125a expression with respect to its target genes LIFR, ERBB2 and STAT3 in the pathogenesis of recurrent pregnancy losses.

Usma ManzoorArshad A PandithIna AminSaima WaniShahid M BabaUmer M WaniSheikh MansoorQurat Ul AeinIqra AnwarBarjista BaharAabid M KoulDheera SanadhyaAbida Ahmad

Published in: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (2024)

The overall conclusion of the study was that altered miR-125a expression may cause deregulation in target genes LIFR, ERBB2 and STAT3 resulting in adverse consequence in the outcome of pregnancy.

Keyphrases

cell proliferation
poor prognosis
long non coding rna
genome wide
long noncoding rna
preterm birth
tyrosine kinase
pregnancy outcomes
binding protein
bioinformatics analysis
genome wide identification
emergency department
genome wide analysis