Biomarkers in Usher syndrome: ultra-widefield fundus autofluorescence and optical coherence tomography findings and their correlation with visual acuity and electrophysiology findings.

Nina MustaficFederica RistoldoVuong NguyenClare L FraserAlessandro InvernizziRobyn V JamiesonJohn R B Grigg

Published in: Documenta ophthalmologica. Advances in ophthalmology (2020)

Structural changes identified on OCT and UW-FAF correlated with BCVA and pERG in this cohort representing different stages of the disease. These parameters could represent reliable biomarkers in therapeutic clinical trials on USH.

Keyphrases

optical coherence tomography
diabetic retinopathy
clinical trial
high resolution
optic nerve
case report
randomized controlled trial
mass spectrometry
open label
placebo controlled