Circulating microbial small RNAs are altered in patients with rheumatoid arthritis.

Michelle J OrmsethQiong WuShilin ZhaoRyan M AllenJoseph SolusQuanhu ShengYan GuoFei YeMarisol Ramirez-SolanoS Louis BridgesJeffrey R CurtisKasey VickersC Michael Stein

Published in: Annals of the rheumatic diseases (2020)

Plasma microbial sRNA composition is altered in RA versus control subjects and associated with some measures of RA disease activity. DMARD treatment does not alter microbial sRNA abundance or composition, but increased abundance of microbial sRNAs at baseline was associated with disease activity improvement at 6 months.

Keyphrases

disease activity
rheumatoid arthritis
systemic lupus erythematosus
microbial community
rheumatoid arthritis patients
ankylosing spondylitis
juvenile idiopathic arthritis
antibiotic resistance genes
wastewater treatment
anaerobic digestion