Elevated exosome-derived miRNAs predict osimertinib resistance in non-small cell lung cancer.
Xinying LiCen ChenZimu WangJiaxin LiuWei SunKaikai ShenYanling LvSuhua ZhuPing ZhanTangfeng LvYong SongPublished in: Cancer cell international (2021)
The expression levels of miR-184 and miR-3913-5p derived from exosomes in the peripheral blood of NSCLC patients could be used as biomarkers to indicate osimertinib resistance.
Keyphrases
- small cell lung cancer
- advanced non small cell lung cancer
- peripheral blood
- end stage renal disease
- poor prognosis
- epidermal growth factor receptor
- ejection fraction
- cell proliferation
- chronic kidney disease
- long non coding rna
- newly diagnosed
- stem cells
- peritoneal dialysis
- prognostic factors
- brain metastases
- patient reported outcomes
- long noncoding rna
- binding protein
- patient reported