Efficacy and Safety of Interferon-Gamma in Chronic Granulomatous Disease: a Systematic Review and Meta-analysis.

Saul Oswaldo Lugo-ReyesAlejandro González GarayNorma Yvett González BobadillaDiana Alejandra Rivera LizárragaAraceli Catalina Madrigal PazEdgar Alejandro Medina-TorresAristóteles Álvarez CardonaJosé Luis Galindo OrtegaCecilia Solís GaliciaSara Elva Espinosa-PadillaChiharu Murata

Published in: Journal of clinical immunology (2022)

The results from this meta-analysis support the use of IFN-γ in the treatment of patients with CGD. However, we found insufficient clinical evidence and believe more clinical trials are needed to better assess the efficacy and long-term safety of IFN-γ.

Keyphrases

dendritic cells
systematic review
clinical trial
immune response
meta analyses
interstitial lung disease
randomized controlled trial
systemic sclerosis
double blind