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Efficacy and Safety of Interferon-Gamma in Chronic Granulomatous Disease: a Systematic Review and Meta-analysis.

Saul Oswaldo Lugo-ReyesAlejandro González GarayNorma Yvett González BobadillaDiana Alejandra Rivera LizárragaAraceli Catalina Madrigal PazEdgar Alejandro Medina-TorresAristóteles Álvarez CardonaJosé Luis Galindo OrtegaCecilia Solís GaliciaSara Elva Espinosa-PadillaChiharu Murata
Published in: Journal of clinical immunology (2022)
The results from this meta-analysis support the use of IFN-γ in the treatment of patients with CGD. However, we found insufficient clinical evidence and believe more clinical trials are needed to better assess the efficacy and long-term safety of IFN-γ.
Keyphrases
  • dendritic cells
  • systematic review
  • clinical trial
  • immune response
  • meta analyses
  • interstitial lung disease
  • randomized controlled trial
  • systemic sclerosis
  • double blind