Electrochemical-induced solvent-tuned selective C(sp 3 )-H bond activation towards the synthesis of C3-functionalized chromone derivatives.
Ying GaoMingxu WangJingxian SunXiao-Jing ZhaoYonghui HePublished in: Chemical communications (Cambridge, England) (2024)
An unprecedented solvent-tuned electrochemical method for selective C(sp 3 )-H bond activation towards the synthesis of C3 functionalized chromone derivatives has been developed. This electrosynthesis protocol provides an efficient and green way to access various C3-functionalized chromones by avoiding traditionally employed transition metals and high temperatures. The swappable chemoselectivity was controlled mainly by altering the solvent and the current. A plausible reaction mechanism has been proposed with the help of radical capture and cyclic voltammetry experiments.
Keyphrases
- ionic liquid
- molecularly imprinted
- quantum dots
- gold nanoparticles
- electron transfer
- solid phase extraction
- randomized controlled trial
- high glucose
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- structure activity relationship
- risk assessment
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- transition metal
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- mass spectrometry
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- drinking water