[Morphological and immunohistochemical predictors of renal response to therapy patients with myeloma cast nephropathy and dialysis-dependent acute kidney injury].
I G RekhtinaE V KazarinaEkaterina StoljarevichA M KovriginaValentina DvirnykS M KulikovL P MendeleevaPublished in: Terapevticheskii arkhiv (2020)
If the interstitial fibrosis area is 40% or more and the expression area of E-cadherin is less than 10%, the probability of the absence of a renal response is 93.3% (OR=24.5) even when a hematological response to induction therapy is achieved. The number of protein casts, the prevalence of acute tubular damage and inflammatory interstitial infiltration have not prognostic value.