Kinome-Wide siRNA Screening Identifies DYRK1B as a Potential Therapeutic Target for Triple-Negative Breast Cancer Cells.

Chia-Che ChangChien-Chih ChiuPei-Feng LiuChih-Hsuan WuYen-Chiang TsengCheng-Hsin LeeChih-Wen Shu

Published in: Cancers (2021)

our results suggest DYRK1B might be essential for promoting tumor progression and could be a theranostic target for TNBC. Silencing or inactivation of DYRK1B might be a potential targeted therapy for TNBC.

Keyphrases

breast cancer cells
cancer therapy
poor prognosis
human health
genome wide
fluorescence imaging
hyaluronic acid