Treatment and Outcome of Autoimmune Hepatitis (AIH): Audit of 28 UK centres.
Victoria Mary GordonRatul AdhikaryVictoria ApplebyDebasish DasJames DayToby DelahookeSelena DixonDavid ElphickClaire HardieMichael A HeneghanBarbara HoeroldtPatricia HooperJohn HutchinsonRebecca JonesFaisal KhanGuruprasad Padur AithalJane MetcalfAlick NkhomaStavroula PelitariMartin PrinceAnnell ProsserVinay SathyanarayanaSushma SaksenaDeven VaniAndrew YeomanGeorge AboudaAndrew NelsonDermot Gleesonnull nullPublished in: Liver international : official journal of the International Association for the Study of the Liver (2022)
We observed higher death/transplant rates in patients with AIH who were untreated with steroids (including asymptomatic or non-cirrhotic sub-groups), those receiving higher Prednisolone doses and those who did not receive an SSA. Similar death/transplant rates were seen in those receiving Prednisolone or Budesonide, those continuing steroids after 12-months and patients attaining normal ALT within 12-months versus not.