Mediation of the association between obesity and osteoarthritis by blood pressure, vessel wall stiffness and subclinical atherosclerosis.

Marieke LoefRob J van der GeestHildo J LambRenée de MutsertSaskia le CessieFrits R RosendaalMargreet Kloppenburg

Published in: Rheumatology (Oxford, England) (2021)

cIMT and diastolic blood pressure minimally mediated the association of BMI with OA. This suggests that such mediation is trivial in the middle-aged population.

Keyphrases

blood pressure
middle aged
hypertensive patients
heart rate
social support
knee osteoarthritis
weight gain
metabolic syndrome
insulin resistance
weight loss
type diabetes
rheumatoid arthritis
left ventricular
high fat diet induced
blood glucose
adipose tissue
skeletal muscle
physical activity