15-Gene Expression Profile and PRAME as Integrated Prognostic Test for Uveal Melanoma: First Report of Collaborative Ocular Oncology Group Study No. 2 (COOG2.1).
J William HarbourZélia M CorreaAmy C ScheflerPrithvi MruthyunjayaMiguel A MaterinThomas A AabergAlison H SkaletDavid A ReichsteinEzekiel WeisIvana K KimTimothy S FullerHakan DemirciKisha D PiggottBasil K WilliamsYevgeniy Eugene ShildkrotAntonio CaponeScott C OliverScott D WalterJohn MasonDevron H CharMichael M AltaweelJill R WellsJay S DukerPeter G HovlandDan S GombosTony TsaiCameron JavidBrian P MarrAng GaoChristina L DecaturJames J DollarStefan KurtenbachStefan KurtenbachPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
classifier over 15-GEP alone and clinical prognostic variables. Tumor diameter was found to be the only clinical variable to provide additional prognostic information. This prognostic classifier provides an advanced resource for risk-adjusted metastatic surveillance and adjuvant trial stratification in patients with UM.