J William Harbour

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 29

Top Venues

Oncogene

Cancers

Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular cancer research : MCR

Sylvester Comprehensive Cancer Center

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Sylvester Comprehensive Cancer Center Jul 01 2014

United States

Associate Director for Basic Research

Bascom Palmer Eye Institute Sep 01 2012

United States

Professor & Vice Chairman

Washington University in St. Louis Jul 01 1996 - Aug 31 2012

United States

Distinguished Professor :: Ophthalmology & Visual Sciences, Medicine and Cell Biology & Physiology

Publications

J William Harbour, Zélia M Correa, Amy C Schefler, Prithvi Mruthyunjaya, Miguel A Materin, Thomas A Aaberg, Alison H Skalet, David A Reichstein, Ezekiel Weis, Ivana K Kim, Timothy S Fuller, Hakan Demirci, Kisha D Piggott, Basil K Williams, Yevgeniy Eugene Shildkrot, Antonio Capone, Scott C Oliver, Scott D Walter, John Mason, Devron H Char, Michael M Altaweel, Jill R Wells, Jay S Duker, Peter G Hovland, Dan S Gombos, Tony Tsai, Cameron Javid, Brian P Marr, Ang Gao, Christina L Decatur, James J Dollar, Stefan Kurtenbach, Stefan Kurtenbach
15-Gene Expression Profile and PRAME as Integrated Prognostic Test for Uveal Melanoma: First Report of Collaborative Ocular Oncology Group Study No. 2 (COOG2.1). Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
J William Harbour, Zélia M Correa, Amy C Schefler, Prithvi Mruthyunjaya, Miguel A Materin, Thomas A Aaberg, Alison H Skalet, David A Reichstein, Ezekiel Weis, Ivana K Kim, Timothy S Fuller, Hakan Demirci, Kisha D Piggott, Basil K Williams, Yevgeniy Eugene Shildkrot, Antonio Capone, Scott C Oliver, Scott D Walter, John Mason, Devron H Char, Michael M Altaweel, Jill R Wells, Jay S Duker, Peter G Hovland, Dan S Gombos, Tony Tsai, Cameron Javid, Brian P Marr, Ang Gao, Christina L Decatur, James J Dollar, Stefan Kurtenbach, Stefan Kurtenbach
15-Gene Expression Profile and PRAME as Integrated Prognostic Test for Uveal Melanoma: First Report of Collaborative Ocular Oncology Group Study No. 2 (COOG2.1). Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Anna Han, Dzmitry Mukha, Vivian Chua, Timothy J Purwin, Manoela Tiago, Bhavik Modasia, Usman Baqai, Jenna L Aumiller, Nelisa Bechtel, Emily Hunter, Meggie Danielson, Mizue Terai, Philip B Wedegaertner, Takami Sato, Solange Landreville, Michael A Davies, Stefan Kurtenbach, J William Harbour, Zachary T Schug, Andrew E Aplin
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth. Cancers 15 (13) (2023)
Jackson R Richards, Donghan Shin, Rob Pryor, Lise K Sorensen, Zhonglou Sun, Won Mi So, Garam Park, Roger Wolff, Amanda Truong, Martin McMahon, Allie H Grossmann, J William Harbour, Weiquan Zhu, Shannon J Odelberg, Jae Hyuk Yoo
Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis. Oncogene (2023)
Stefan Kurtenbach, Margaret I Sanchez, Jeffim Kuznetsoff, Daniel A Rodriguez, Natalia Weich, James J Dollar, Anthony Cruz, Sarah Kurtenbach, Matthew G Field, Michael A Durante, Christina L Decatur, Mahsa Sorouri, Fan Lai, Gulum Yenisehirli, Bin Fang, Ramin Shiekhattar, Daniel Pelaez, Zelia M Correa, Ramiro E Verdun, J William Harbour
PRAME induces genomic instability in uveal melanoma. Oncogene (2023)
Jackson R Richards, Donghan Shin, Rob Pryor, Lise K Sorensen, Zhonglou Sun, Won Mi So, Garam Park, Roger Wolff, Amanda Truong, Martin McMahon, Allie H Grossmann, J William Harbour, Weiquan Zhu, Shannon J Odelberg, Jae Hyuk Yoo
Correction: Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis. Oncogene (2023)
Anna Han, Vivian Chua, Usman Baqai, Timothy J Purwin, Nelisa Bechtel, Emily Hunter, Manoela Tiago, Erin Seifert, David W Speicher, Zachary T Schug, J William Harbour, Andrew E Aplin
Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma. Oncogene 41 (8) (2022)
Christopher J Kaler, James J Dollar, Anthony M Cruz, Jeffim N Kuznetsoff, Margaret I Sanchez, Christina L Decatur, Jonathan D Licht, Keiran S M Smalley, Zelia M Correa, Stefan Kurtenbach, J William Harbour
BAP1 Loss Promotes Suppressive Tumor Immune Microenvironment via Upregulation of PROS1 in Class 2 Uveal Melanomas. Cancers 14 (15) (2022)
Usman Baqai, Timothy J Purwin, Nelisa Bechtel, Vivian Chua, Anna Han, Edward J Hartsough, Jeffim N Kuznetsov, J William Harbour, Andrew E Aplin
Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma. Molecular cancer research : MCR 20 (8) (2022)
Michelle G Zhang, Jeffim N Kuznetsoff, Dawn A Owens, Ryan A Gallo, Karthik Kalahasty, Anthony M Cruz, Stefan Kurtenbach, Zelia M Correa, Daniel Pelaez, J William Harbour
Early Mechanisms of Chemoresistance in Retinoblastoma. Cancers 14 (19) (2022)
Matthew G Field, Jeffim N Kuznetsov, Michelle G Zhang, James J Dollar, Michael A Durante, Yoseph Sayegh, Christina L Decatur, Stefan Kurtenbach, Daniel Pelaez, J William Harbour
RB1 loss triggers dependence on ESRRG in retinoblastoma. Science advances 8 (33) (2022)
Stefan Kurtenbach, James J Dollar, Anthony M Cruz, Michael A Durante, Christina L Decatur, J William Harbour
PieParty: visualizing cells from scRNA-seq data as pie charts. Life science alliance 4 (5) (2021)
Hongzhuang Peng, Joel Cassel, Daniel S McCracken, Jeremy W Prokop, Eleonora Sementino, Mitchell Cheung, Paul R Collop, Alexander Polo, Surbhi Joshi, Jacob P Mandell, Kasirajan Ayyanathan, David Hinds, S Bruce Malkowicz, J William Harbour, Anne M Bowcock, Joseph M Salvino, Eileen J Kennedy, Joseph R Testa, Frank J Rauscher
Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase. Molecular cancer research : MCR 19 (7) (2021)
Stefan Kurtenbach, Anthony M Cruz, Daniel A Rodriguez, Michael A Durante, J William Harbour
Uphyloplot2: visualizing phylogenetic trees from single-cell RNA-seq data. BMC genomics 22 (1) (2021)
J William Harbour
Therapeutic Escape in Gαq-mutant Uveal Melanoma: It's a FAK. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (11) (2021)
Vivian Chua, Anna Han, Nelisa Bechtel, Timothy J Purwin, Emily Hunter, Connie Liao, J William Harbour, Andrew E Aplin
The AMP-dependent kinase pathway is upregulated in BAP1 mutant uveal melanoma. Pigment cell & melanoma research (2021)
Daniel A Rodriguez, Jessica Yang, Michael A Durante, Alexander N Shoushtari, Stergios J Moschos, Kazimierz O Wrzeszczynski, J William Harbour, Richard D Carvajal
Multiregional genetic evolution of metastatic uveal melanoma. NPJ genomic medicine 6 (1) (2021)
Michael A Durante, Daniel A Rodriguez, Stefan Kurtenbach, Jeffim N Kuznetsov, Margaret I Sanchez, Christina L Decatur, Helen Snyder, Lynn G Feun, Alan S Livingstone, J William Harbour
Single-cell analysis reveals new evolutionary complexity in uveal melanoma. Nature communications 11 (1) (2020)
Daniel A Rodriguez, Margaret I Sanchez, Christina L Decatur, Zélia M Correa, Eden R Martin, J William Harbour
Impact of Genetic Ancestry on Prognostic Biomarkers in Uveal Melanoma. Cancers 12 (11) (2020)
Konstantinos E Hatzistergos, Michael A Durante, Krystalenia Valasaki, Amarylis C B A Wanschel, J William Harbour, Joshua M Hare
A novel cardiomyogenic role for Isl1+ neural crest cells in the inflow tract. Science advances 6 (49) (2020)
Anna M Armitage, Monica A Kundra, Neda Ghiam, Paldeep S Atwal, Dayna Morel, Kathleen S Hruska, Rebecca Torene, J William Harbour, Irman Forghani
Chimerism involving a RB1 pathogenic variant in monochorionic dizygotic twins with twin-twin transfusion syndrome. American journal of medical genetics. Part A 185 (1) (2020)
Jeffim N Kuznetsov, Dawn A Owens, Andy Lopez, Daniel A Rodriguez, Nancy T Chee, Stefan Kurtenbach, Daniel Bilbao, Evan R Roberts, Claude-Henry Volmar, Claes Wahlestedt, Shaun P Brothers, J William Harbour
Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma. Molecular cancer research : MCR 19 (2) (2020)
Fernanda Faião-Flores, Michael F Emmons, Michael A Durante, Fumi Kinose, Biswarup Saha, Bin Fang, John M Koomen, Srikumar P Chellappan, Silvya Stuchi Maria-Engler, Uwe Rix, Jonathan D Licht, J William Harbour, Keiran S M Smalley
HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (18) (2019)
Matthew G Field, Jeffim N Kuznetsov, Parker L Bussies, Louie Z Cai, Karam A Alawa, Christina L Decatur, Stefan Kurtenbach, J William Harbour
BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (18) (2019)
Jeffim N Kuznetsov, Tristan H Aguero, Dawn A Owens, Stefan Kurtenbach, Matthew G Field, Michael A Durante, Daniel A Rodriguez, Mary Lou King, J William Harbour
BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers. Science advances 5 (9) (2019)
Michael A Durante, Matthew G Field, Margaret I Sanchez, Kyle R Covington, Christina L Decatur, Sander R Dubovy, J William Harbour
Genomic evolution of uveal melanoma arising in ocular melanocytosis. Cold Spring Harbor molecular case studies 5 (4) (2019)
Hima Anbunathan, Ruth Verstraten, Arun D Singh, J William Harbour, Anne M Bowcock
Integrative Copy Number Analysis of Uveal Melanoma Reveals Novel Candidate Genes Involved in Tumorigenesis Including a Tumor Suppressor Role for PHF10/BAF45a. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (16) (2019)
Ying Guo, Hui Yang, Shi Chen, Peng Zhang, Rong Li, Stephen D Nimer, J William Harbour, Mingjiang Xu, Feng-Chun Yang
Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo. Leukemia 32 (8) (2018)
Matthew G Field, Michael A Durante, Hima Anbunathan, Louis Z Cai, Christina L Decatur, Anne M Bowcock, Stefan Kurtenbach, J William Harbour
Punctuated evolution of canonical genomic aberrations in uveal melanoma. Nature communications 9 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

J William Harbour