Characterization of muscle strength and mobility in oculopharyngeal muscular dystrophy.
Jean-Denis BrissonBernard BraisJean MathieuIsabelle LessardValérie Gagné-OuelletIsabelle CôtéCynthia GagnonPublished in: Muscle & nerve (2023)
This study highlights the impact of OPMD on strength, endurance, and functional capacity, among others, with patients being well below reference values even before the age of 65 y. In addition to helping health professionals to offer better clinical guidance, these results will improve clinical trial readiness. The next steps will be to assess the metrological properties of outcome measures and continue to document the disease progression rate.
Keyphrases
- muscular dystrophy
- clinical trial
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- duchenne muscular dystrophy
- skeletal muscle
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- patient reported outcomes
- open label
- high intensity
- resistance training
- patient reported
- phase iii