The role of pro-opiomelanocortin in the ACTH-cortisol dissociation of sepsis.

Greet Van den BergheSarah Vander PerreLies PauwelsSarah DerdeTim Van OudenhoveLies Langouche Greet Van den Berghe

Published in: Critical care (London, England) (2021)

Together, these findings suggest that increased circulating POMC, through CRH/AVP-driven POMC expression and impaired processing into ACTH, could represent a new piece in the puzzling ACTH-cortisol dissociation.

Keyphrases

poor prognosis
electron transfer
intensive care unit
acute kidney injury
septic shock
anti inflammatory