Comprehensive and comparative studies on nanocytotoxicity of glyceryl monooleate- and phytantriol-based lipid liquid crystalline nanoparticles.

Jakub JagielskiŁucja PrzysieckaDorota FlakMagdalena DiakZuzanna Pietralik-MolińskaMaciej KozakStefan JurgaGrzegorz Nowaczyk

Published in: Journal of nanobiotechnology (2021)

Overall, GMO-based LLCNPs emerge as potentially more viable candidates for drug delivery systems as their impact on cells is not as deleterious as PHT-based as well as they were efficiently internalized by cell monolayers and 3D spheroids.

Keyphrases

induced apoptosis
cell cycle arrest
single cell
room temperature
fatty acid
stem cells
endoplasmic reticulum stress
ionic liquid
oxidative stress
cell death
signaling pathway