Differential DNA methylation in iPSC-derived dopaminergic neurons: a step forward on the role of SNORD116 microdeletion in the pathophysiology of addictive behavior in Prader-Willi syndrome.

Juliette SallesSanaa EddirySaber AmriMélissa GalindoEmmanuelle LacassagneSimon GeorgeXavier MialheÉmeline LhuillierNicolas FranchittoFreddy JeanneteauIsabelle GenneroJean Pierre Salles Maïthé Tauber

Published in: Molecular psychiatry (2024)

SNORD116 MD dopaminergic neurons displayed differential methylation and expression in the COMT and SLC6A3 genes, which are related to dopaminergic clearance.

Keyphrases

dna methylation
genome wide
spinal cord
poor prognosis
growth hormone
molecular dynamics
case report
long non coding rna
binding protein
drug induced