AKT1/HK2 Axis-mediated Glucose Metabolism: A Novel Therapeutic Target of Sulforaphane in Bladder Cancer.

Lei HuangCanxia HeSicong ZhengChao WuMinghua RenYujuan Shan

Published in: Molecular nutrition & food research (2021)

SFN downregulates the unique glucose transport aberrant-independent aerobic glycolysis existed in bladder cancer via blocking the AKT1/HK2 axis and PDH expression.

Keyphrases

signaling pathway
cell proliferation
poor prognosis
high glucose
binding protein
blood glucose
endothelial cells
adipose tissue
muscle invasive bladder cancer
long non coding rna
type diabetes
blood pressure
weight loss