Sex differences and sex steroids influence on the presentation and severity of cardiovascular autonomic neuropathy of patients with type 1 diabetes.
Lía Nattero-ChávezMaría InsenserAlejandra Quintero TobarElena Fernández-DuránBeatriz Dorado AvendañoTom FiersJean-Marc KaufmanManuel Luque-RamírezHéctor F Escobar-MorrealePublished in: Cardiovascular diabetology (2023)
Menopause in women with type 1 diabetes is accompanied by an increase in the prevalence of asymptomatic cardioautonomic neuropathy. This age-related excess risk of cardioautonomic neuropathy is not observed in men. Men and women with type 1 diabetes have opposite associations between circulating androgens and indexes of cardioautonomic function. Trial registration ClinicalTrials.gov Identifier: NCT04950634.