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The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells.
Wu-Ying Du
Zhen-Hai Lu
Wen Ye
Xiang Fu
Yi Zhou
Chun-Mei Kuang
Jiang-Xue Wu
Zhi-Zhong Pan
Shuai Chen
Ran-Yi Liu
Wen-Lin Huang
Published in:
Chinese journal of cancer (2017)
ASB3 dysfunction resulted from gene mutations or down-regulated expression frequently exists in CRC and likely plays a key role in the pathogenesis and progression of CRC.
Keyphrases
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poor prognosis
transcription factor
oxidative stress
copy number
long non coding rna