Engineered extracellular matrices facilitate brain organoids from human pluripotent stem cells.
Ayşe J MuñizTuğba TopalMichael D BrooksAngela SzeDo Hoon KimJacob JordahlJoe NguyenPaul H KrebsbachMasha Georges SavelieffEva L FeldmanJoerg LahannPublished in: Annals of clinical and translational neurology (2023)
Engineered EECM matrices represent a major advancement in neural engineering as they have the potential to significantly enhance the structural, cellular, and functional diversity that can be achieved in advanced brain models.