MiRNA-224-5p regulates the defective permeability barrier in sensitive skin by targeting claudin-5.
Li YangWen-Juan WuLe-Chun LyuYing TuHua GuXiang-Feng ChenYan-Jie ChaiMao-Qiang ManLi HePublished in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2024)
These results suggest that the miR-224-5p-induced reduction in CLDN5 expression leads to impaired permeability barrier function, and that miR-224-5p could be a potential therapeutic target for sensitive skin.