Prospective randomized comparison between upgraded '2C3L' vs. PVI approach for catheter ablation of persistent atrial fibrillation: PROMPT-AF trial design.

Xiao-Xia LiuQiang LiuYi-Wei LaiQi GuoRong BaiDe-Yong LongRong-Hui YuRi-Bo TangNian LiuChen-Xi JiangWei WangXue-Yuan GuoSong-Nan LiXin ZhaoSong ZuoChang-Yi LiShang-Ming SongShuang-Lun XieWei-Li GeJian-Gang ZouXiao-Feng HouKe ChenJin-Lin ZhangHe-Sheng HuXin-Hua WangZhao-Jun WangXin DuChen-Yang JiangCai-Hua SangJian-Zeng DongChang-Sheng Ma

Published in: American heart journal (2023)

The PROMPT-AF study will evaluate the efficacy of the fixed '2C3L' approach in conjunction with EI-VOM, compared with PVI alone, in patients with PeAF undergoing de novo ablation.

Keyphrases

atrial fibrillation
catheter ablation
left atrial
left atrial appendage
oral anticoagulants
phase iii
direct oral anticoagulants
phase ii
heart failure
open label
double blind
clinical trial
study protocol
placebo controlled
left ventricular
randomized controlled trial
mitral valve